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A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5953516

A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

About this item

Full title

A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2018-02, Vol.359 (6377), p.770-775

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

Immune checkpoint inhibitors induce durable tumor regressions in some, but not all, cancer patients. Understanding the mechanisms that determine tumor sensitivity to these drugs could potentially expand the number of patients who benefit (see the Perspective by Ghorani and Quezada). Pan
et al.
discovered that tumor cells in which a specific S...

Alternative Titles

Full title

A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5953516

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5953516

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aao1710

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