An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease
An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Mutations leading to premature termination codons in ATP-Binding Cassette Subfamily A Member 7 (
ABCA7
) are high penetrant risk factors of Alzheimer’s disease (AD). The influence of other genetic variants in
ABCA7
and downstream functional mechanisms, however, is poorly understood. To address this knowledge gap, we investigated tandem...
Alternative Titles
Full title
An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5954066
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5954066
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-018-1841-z
