Translocation of a gut pathobiont drives autoimmunity in mice and humans
Translocation of a gut pathobiont drives autoimmunity in mice and humans
About this item
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Author / Creator
Manfredo Vieira, S , Hiltensperger, M , Kumar, V , Zegarra-Ruiz, D , Dehner, C , Khan, N , Costa, F R C , Tiniakou, E , Greiling, T , Ruff, W , Barbieri, A , Kriegel, C , Mehta, S S , Knight, J R , Jain, D , Goodman, A L and Kriegel, M A
Publisher
United States: The American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: The American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Despite multiple associations between the microbiota and immune diseases, their role in autoimmunity is poorly understood. We found that translocation of a gut pathobiont,
, to the liver and other systemic tissues triggers autoimmune responses in a genetic background predisposing to autoimmunity. Antibiotic treatment prevented mortality in this...
Alternative Titles
Full title
Translocation of a gut pathobiont drives autoimmunity in mice and humans
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5959731
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5959731
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aar7201
