OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos
OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Oxidative stress-induced DNA damage has been well acknowledged as a major cause leading to cell death, which is etiologically linked to ischemic injury and degenerative alterations. The most common oxidation product of DNA is base lesion 8-oxo-7,8-dihydroguanine (8-oxoG), which is repaired by 8-oxoG glycosylase1 (OGG1)-initiated baseexcision repair...
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Full title
OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5967321
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5967321
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-018-0680-0
