Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoho...
Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Accumulating evidence has suggested that farnesoid X receptor (FXR) agonists, such as obeticholic acid (OCA) are therapeutically useful for non-alcoholic steatohepatitis (NASH). However, it is still unclear how FXR agonists protect against NASH and which cell type is the main target of FXR agonists. In this study, we examined the effects of OCA on...
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Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5970222
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5970222
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-26383-8
