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Allosteric Activation of GDP-Bound Ras Isoforms by Bisphenol Derivative Plasticisers

Allosteric Activation of GDP-Bound Ras Isoforms by Bisphenol Derivative Plasticisers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5979466

Allosteric Activation of GDP-Bound Ras Isoforms by Bisphenol Derivative Plasticisers

About this item

Full title

Allosteric Activation of GDP-Bound Ras Isoforms by Bisphenol Derivative Plasticisers

Publisher

Switzerland: MDPI

Journal title

International journal of molecular sciences, 2018-04, Vol.19 (4), p.1133

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

The protein family of small GTPases controls cellular processes by acting as a binary switch between an active and an inactive state. The most prominent family members are H-Ras, N-Ras, and K-Ras isoforms, which are highly related and frequently mutated in cancer. Bisphenols are widespread in modern life because of their industrial application as p...

Alternative Titles

Full title

Allosteric Activation of GDP-Bound Ras Isoforms by Bisphenol Derivative Plasticisers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5979466

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5979466

Other Identifiers

ISSN

1422-0067

E-ISSN

1422-0067

DOI

10.3390/ijms19041133

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