β-Amyloid Peptides Enhance α-Synuclein Accumulation and Neuronal Deficits in a Transgenic Mouse Mode...
β-Amyloid Peptides Enhance α-Synuclein Accumulation and Neuronal Deficits in a Transgenic Mouse Model Linking Alzheimer's Disease and Parkinson's Disease
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Alzheimer's disease and Parkinson's disease are associated with the cerebral accumulation of β-amyloid and α-synuclein, respectively. Some patients have clinical and pathological features of both diseases, raising the possibility of overlapping pathogenetic pathways. We generated transgenic (tg) mice with neuronal expression of human β-amyloid pept...
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β-Amyloid Peptides Enhance α-Synuclein Accumulation and Neuronal Deficits in a Transgenic Mouse Model Linking Alzheimer's Disease and Parkinson's Disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_59799
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_59799
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.211412398