Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice a...
Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Human mPGES-1 is recognized as a promising target for next generation of anti-inflammatory drugs without the side effects of currently available anti-inflammatory drugs, and various inhibitors have been reported in the literature. However, none of the reported potent inhibitors of human mPGES-1 has shown to be also a potent inhibitor of mouse or ra...
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Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5979965
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5979965
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-23482-4
