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MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells

MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5984507

MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells

About this item

Full title

MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (22), p.5768-5773

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Glioma stem cells (GSCs) comprise a small subpopulation of glioblastoma multiforme cells that contribute to therapy resistance, poor prognosis, and tumor recurrence. Protective autophagy promotes resistance of GSCs to anoikis, a form of programmed cell death occurring when anchorage-dependent cells detach from the extracellular matrix. In nonadhere...

Alternative Titles

Full title

MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5984507

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5984507

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1721650115

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