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Humanized mice reveal an essential role for human hepatocytes in the development of the liver immune...

Humanized mice reveal an essential role for human hepatocytes in the development of the liver immune...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5986801

Humanized mice reveal an essential role for human hepatocytes in the development of the liver immune system

About this item

Full title

Humanized mice reveal an essential role for human hepatocytes in the development of the liver immune system

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2018-06, Vol.9 (6), p.667-10, Article 667

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The liver is an immunological organ with a distinct immune cell profile. Although the composition and function of liver immune cells have been widely investigated, the mechanisms regulating the development and homeostasis of the specialized immune system, especially in humans, remain largely unknown. Herein, we address this question in humanized mi...

Alternative Titles

Full title

Humanized mice reveal an essential role for human hepatocytes in the development of the liver immune system

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5986801

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5986801

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-018-0720-9

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