Compound CAR T-cells as a double-pronged approach for treating acute myeloid leukemia
Compound CAR T-cells as a double-pronged approach for treating acute myeloid leukemia
About this item
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Author / Creator
Petrov, Jessica C. , Wada, Masayuki , Pinz, Kevin G. , Yan, Lulu E. , Chen, Kevin H. , Shuai, Xiao , Liu, Hua , Chen, Xi , Leung, Lai-Han , Salman, Huda , Hagag, Nabil , Liu, Fang , Jiang, Xun and Ma, Yupo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Acute myeloid leukemia (AML) bears heterogeneous cells that can consequently offset killing by single-CAR-based therapy, which results in disease relapse. Leukemic stem cells (LSCs) associated with CD123 expression comprise a rare population that also plays an important role in disease progression and relapse. Here, we report on the robust anti-tum...
Alternative Titles
Full title
Compound CAR T-cells as a double-pronged approach for treating acute myeloid leukemia
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5990523
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5990523
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-018-0075-3
