Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice
Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice
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Author / Creator
Wang, Jingxiao , Dong, Mingjie , Xu, Zhong , Song, Xinhua , Zhang, Shanshan , Qiao, Yu , Che, Li , Gordan, John , Hu, Kaiwen , Liu, Yan , Calvisi, Diego F. and Chen, Xin
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Liver cancer comprises a group of malignant tumors, among which hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the most common. ICC is especially pernicious and associated with poor clinical outcome. Studies have shown that a subset of human ICCs may originate from mature hepatocytes. However, the mechanisms driving th...
Alternative Titles
Full title
Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6002343
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6002343
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-018-0188-1