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Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice

Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6002343

Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice

About this item

Full title

Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2018-06, Vol.37 (24), p.3229-3242

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Liver cancer comprises a group of malignant tumors, among which hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the most common. ICC is especially pernicious and associated with poor clinical outcome. Studies have shown that a subset of human ICCs may originate from mature hepatocytes. However, the mechanisms driving th...

Alternative Titles

Full title

Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6002343

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6002343

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-018-0188-1

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