Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small inte...
Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The hallmark features of type 2 mucosal immunity include intestinal tuft and goblet cell expansion initiated by tuft cell activation. How infectious agents that induce type 2 mucosal immunity are detected by tuft cells is unknown. Published microarray analysis suggested that succinate receptor 1 (Sucnr1) is specifically expressed in tuft cells. Thu...
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Full title
Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6003470
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6003470
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1720758115
