Codon usage of highly expressed genes affects proteome-wide translation efficiency
Codon usage of highly expressed genes affects proteome-wide translation efficiency
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Although the genetic code is redundant, synonymous codons for the same amino acid are not used with equal frequencies in genomes, a phenomenon termed “codon usage bias.” Previous studies have demonstrated that synonymous changes in a coding sequence can exert significant cis effects on the gene’s expression level. However, whether the codon composi...
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Full title
Codon usage of highly expressed genes affects proteome-wide translation efficiency
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6003480
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6003480
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1719375115
