The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cance...
The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells
About this item
Full title
Author / Creator
Leithner, Katharina , Triebl, Alexander , Trötzmüller, Martin , Hinteregger, Barbara , Leko, Petra , Wieser, Beatrix I. , Grasmann, Gabriele , Bertsch, Alexandra L. , Züllig, Thomas , Stacher, Elvira , Valli, Alessandro , Prassl, Ruth , Olschewski, Andrea , Harris, Adrian L. , Köfeler, Harald C. , Olschewski, Horst and Hrzenjak, Andelko
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Cancer cells are reprogrammed to consume large amounts of glucose to support anabolic biosynthetic pathways. However, blood perfusion and consequently the supply with glucose are frequently inadequate in solid cancers. PEPCK-M (PCK2), the mitochondrial isoform of phosphoenolpyruvate carboxykinase (PEPCK), has been shown by us and others to be funct...
Alternative Titles
Full title
The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells
Authors, Artists and Contributors
Author / Creator
Triebl, Alexander
Trötzmüller, Martin
Hinteregger, Barbara
Leko, Petra
Wieser, Beatrix I.
Grasmann, Gabriele
Bertsch, Alexandra L.
Züllig, Thomas
Stacher, Elvira
Valli, Alessandro
Prassl, Ruth
Olschewski, Andrea
Harris, Adrian L.
Köfeler, Harald C.
Olschewski, Horst
Hrzenjak, Andelko
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6004450
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6004450
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1719871115