Activated integrins identify functional antigen-specific CD8⁺ T cells within minutes after antigen s...
Activated integrins identify functional antigen-specific CD8⁺ T cells within minutes after antigen stimulation
About this item
Full title
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Immediate β₂-integrin activation upon T cell receptor stimulation is critical for effective interaction between T cells and their targets and may therefore be used for the rapid identification and isolation of functional T cells. We present a simple and sensitive flow cytometry-based assay to assess antigen-specific T cells using fluorescent interc...
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Full title
Activated integrins identify functional antigen-specific CD8⁺ T cells within minutes after antigen stimulation
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6004473
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6004473
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1720714115
