Mice with reduced DAT levels recreate seasonal-induced switching between states in bipolar disorder
Mice with reduced DAT levels recreate seasonal-induced switching between states in bipolar disorder
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Publisher
England: Nature Publishing Group
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Language
English
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Publisher
England: Nature Publishing Group
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Contents
Developing novel therapeutics for bipolar disorder (BD) has been hampered by limited mechanistic knowledge how sufferers switch between mania and depression-how the same brain can switch between extreme states-described as the "holy grail" of BD research. Strong evidence implicates seasonally-induced switching between states, with mania associated...
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Full title
Mice with reduced DAT levels recreate seasonal-induced switching between states in bipolar disorder
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6006292
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6006292
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ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/s41386-018-0031-y
