Formation of Supramolecular Activation Clusters on Fresh ex vivo CD8+T Cells after Engagement of the...
Formation of Supramolecular Activation Clusters on Fresh ex vivo CD8+T Cells after Engagement of the T Cell Antigen Receptor and CD8 by Antigen-Presenting Cells
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Upon productive interaction of CD4 T cells with antigen-presenting cells (APCs), receptors and intracellular proteins translocate and form spatially segregated supramolecular activation clusters (SMACs). It is not known whether SMACs are required for CD8 T cell activation. CD8 T cells, unlike CD4 T cells, can be activated by a single peptide-MHC mo...
Alternative Titles
Full title
Formation of Supramolecular Activation Clusters on Fresh ex vivo CD8+T Cells after Engagement of the T Cell Antigen Receptor and CD8 by Antigen-Presenting Cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_60104
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_60104
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.221458898
