Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate c...
Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription
About this item
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Author / Creator
Jia, Lin , Wu, Dinglan , Wang, Yuliang , You, Wenxing , Wang, Zhu , Xiao, Lijia , Cai, Ganhui , Xu, Zhenyu , Zou, Chang , Wang, Fei , Teoh, Jeremy Yuen-Chun , Ng, Chi-Fai , Yu, Shan and Chan, Franky L.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The metastatic castration-resistant prostate cancer (CRPC) is a lethal form of prostate cancer, in which the expression of androgen receptor (AR) is highly heterogeneous. Indeed, lower AR expression and attenuated AR signature activity is shown in CRPC tissues, especially in the subset of neuroendocrine prostate cancer (NEPC) and prostate cancer st...
Alternative Titles
Full title
Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6013422
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6013422
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-018-0198-z
