Piperlongumine and p53-reactivator APR-246 selectively induce cell death in HNSCC by targeting GSTP1
Piperlongumine and p53-reactivator APR-246 selectively induce cell death in HNSCC by targeting GSTP1
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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TP53 mutations frequently occur in head and neck squamous cell carcinoma (HNSCC) patients without human papillomavirus infection. The recurrence rate for these patients is distinctly high. It has been actively explored to identify agents that target TP53 mutations and restore wild-type (WT) TP53 activities in HNSCC. PRIMA-1 (p53-reactivation and in...
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Piperlongumine and p53-reactivator APR-246 selectively induce cell death in HNSCC by targeting GSTP1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6014869
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6014869
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-017-0110-2
