Metastatic cancers promote cachexia through altered zinc homeostasis in skeletal muscle
Metastatic cancers promote cachexia through altered zinc homeostasis in skeletal muscle
About this item
Full title
Author / Creator
Wang, Gang , Biswas, Anup K. , Ma, Wanchao , Kandpal, Manoj , Coker, Courtney , Grandgenett, Paul M. , Hollingsworth, Michael A. , Jain, Rinku , Tanji, Kurenai , Lόpez-Pintado, Sara , Borczuk, Alain , Hebert, Doreen , Jenkitkasemwong, Supak , Hojyo, Shintaro , Davuluri, Ramana , Knutson, Mitchell D. , Fukada, Toshiyuki and Acharyya, Swarnali
Journal title
Language
English
Formats
More information
Scope and Contents
Contents
Metastatic cancer patients experience a severe loss of skeletal muscle
mass and function known as cachexia. Cachexia is associated with poor prognosis
and accelerated death in cancer patients, yet its underlying mechanisms remain
poorly understood. Here, we identify the metal transporter ZIP14 as a critical
mediator of cancer-induced ca...
Alternative Titles
Full title
Metastatic cancers promote cachexia through altered zinc homeostasis in skeletal muscle
Authors, Artists and Contributors
Author / Creator
Biswas, Anup K.
Ma, Wanchao
Kandpal, Manoj
Coker, Courtney
Grandgenett, Paul M.
Hollingsworth, Michael A.
Jain, Rinku
Tanji, Kurenai
Lόpez-Pintado, Sara
Borczuk, Alain
Hebert, Doreen
Jenkitkasemwong, Supak
Hojyo, Shintaro
Davuluri, Ramana
Knutson, Mitchell D.
Fukada, Toshiyuki
Acharyya, Swarnali
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6015555
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6015555
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-018-0054-2
