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NLRP3 inflammasome is expressed and regulated in human islets

NLRP3 inflammasome is expressed and regulated in human islets

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6018156

NLRP3 inflammasome is expressed and regulated in human islets

About this item

Full title

NLRP3 inflammasome is expressed and regulated in human islets

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2018-06, Vol.9 (7), p.726-10, Article 726

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

NRLP3 inflammasome is a protein complex involved in the maturation of IL1β. In the onset of type 1 diabetes as well as in islet transplantation, IL-1β is one of the cytokines involved in the recruitment of immune cells in islets and eventually in islet destruction. Whether IL-1β is produced by islet cells is still under debate and NLRP3 inflammasom...

Alternative Titles

Full title

NLRP3 inflammasome is expressed and regulated in human islets

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6018156

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6018156

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-018-0764-x

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