Active suppression rather than ignorance: tolerance to abacavir-induced HLA-B57:01 peptide repertoir...
Active suppression rather than ignorance: tolerance to abacavir-induced HLA-B57:01 peptide repertoire alteration
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Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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United States: American Society for Clinical Investigation
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Scope and Contents
Contents
The discovery of HLA-B*57:01-associated abacavir hypersensitivity is a translational success story that eliminated adverse reactions to abacavir through pretreatment screening and defined a mechanistic model of an altered peptide repertoire. In this issue of the JCI, Cardone et al. have developed an HLA-B*57:01-transgenic mouse model and demonstrat...
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Full title
Active suppression rather than ignorance: tolerance to abacavir-induced HLA-B57:01 peptide repertoire alteration
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6025972
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6025972
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI121525
