Loss of protein phosphatase 6 in mouse keratinocytes enhances K‐ras G12D ‐driven tumor promotion
Loss of protein phosphatase 6 in mouse keratinocytes enhances K‐ras G12D ‐driven tumor promotion
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Author / Creator
Kurosawa, Koreyuki , Inoue, Yui , Kakugawa, Yoichiro , Yamashita, Yoji , Kanazawa, Kosuke , Kishimoto, Kazuhiro , Nomura, Miyuki , Momoi, Yuki , Sato, Ikuro , Chiba, Natsuko , Suzuki, Mai , Ogoh, Honami , Yamada, Hidekazu , Miura, Koh , Watanabe, Toshio , Tanuma, Nobuhiro , Tachi, Masahiro and Shima, Hiroshi
Publisher
England: John Wiley and Sons Inc
Journal title
Language
English
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Publication information
Publisher
England: John Wiley and Sons Inc
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Scope and Contents
Contents
Here, we address the function of protein phosphatase 6 (PP6) loss on K‐ras‐initiated tumorigenesis in keratinocytes. To do so, we developed tamoxifen‐inducible double mutant (
K‐ras
G12D
‐expressing and
Ppp6c
‐deficient) mice in which
K‐ras
G12D
expression is driven by the cytokeratin 14 (K14) promoter. Doubly‐mutant mice sh...
Alternative Titles
Full title
Loss of protein phosphatase 6 in mouse keratinocytes enhances K‐ras G12D ‐driven tumor promotion
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6029815
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6029815
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/cas.13638
