Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage...
Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The production of cytokines in response to DNA-damage events may be an important host defense response to help prevent the escape of pre-cancerous cells. The innate immune pathways involved in these events are known to be regulated by cellular molecules such as stimulator of interferon genes (STING), which controls type I interferon and pro-inflamm...
Alternative Titles
Full title
Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6029885
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6029885
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-017-0120-0
