A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics
A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics
About this item
Full title
Author / Creator
Li, Dandan , Mo, Fei , Wu, Jiangling , Huang, Yong , Zhou, Huihao , Ding, Shijia and Chen, Weixian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The highly efficient cancer cell targeted delivery plays an important role in precise targeted therapies. Herein, a multifunctional DNA nano-scorpion nanostructure (termed AptDzy-DNS) functioned with aptamers and DNAzyme is developed for highly efficient targeted delivery of mRNA therapeutics in gene therapy. The designed AptDzy-DNS is self-assembl...
Alternative Titles
Full title
A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6033943
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6033943
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-28542-3