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A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics

A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6033943

A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics

About this item

Full title

A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-07, Vol.8 (1), p.10196-9, Article 10196

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The highly efficient cancer cell targeted delivery plays an important role in precise targeted therapies. Herein, a multifunctional DNA nano-scorpion nanostructure (termed AptDzy-DNS) functioned with aptamers and DNAzyme is developed for highly efficient targeted delivery of mRNA therapeutics in gene therapy. The designed AptDzy-DNS is self-assembl...

Alternative Titles

Full title

A multifunctional DNA nano-scorpion for highly efficient targeted delivery of mRNA therapeutics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6033943

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6033943

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-28542-3

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