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A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatoc...

A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatoc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6035113

A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma

About this item

Full title

A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2018-07, Vol.37 (27), p.3740-3752

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cellular components of solid tumors including DNA are released into the bloodstream, but data on circulating-free DNA (cfDNA) in hepatocellular carcinoma (HCC) are still scarce. This study aimed at analyzing mutations in cfDNA and their correlation with tissue mutations in patients with HCC. We included 8 HCC patients treated with surgical resectio...

Alternative Titles

Full title

A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6035113

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6035113

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-018-0206-3

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