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Human Umbilical Cord Blood Serum–derived α-Secretase: Functional Testing in Alzheimer’s Disease Mous...

Human Umbilical Cord Blood Serum–derived α-Secretase: Functional Testing in Alzheimer’s Disease Mous...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6038040

Human Umbilical Cord Blood Serum–derived α-Secretase: Functional Testing in Alzheimer’s Disease Mouse Models

About this item

Full title

Human Umbilical Cord Blood Serum–derived α-Secretase: Functional Testing in Alzheimer’s Disease Mouse Models

Publisher

Los Angeles, CA: SAGE Publications

Journal title

Cell transplantation, 2018-03, Vol.27 (3), p.438-455

Language

English

Formats

Publication information

Publisher

Los Angeles, CA: SAGE Publications

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Alzheimer’s disease (AD) is an age-related disorder that affects cognition. Our previous studies showed that the neuroprotective fragment of amyloid procurer protein (APP) metabolite, soluble APPα (sAPPα), interferes with β-site APP-cleaving enzyme 1 (BACE1, β-secretase) cleavage and reduces amyloid-β (Aβ) generation. In an attempt to identify appr...

Alternative Titles

Full title

Human Umbilical Cord Blood Serum–derived α-Secretase: Functional Testing in Alzheimer’s Disease Mouse Models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6038040

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6038040

Other Identifiers

ISSN

0963-6897

E-ISSN

1555-3892

DOI

10.1177/0963689718759473

How to access this item