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Inactivating hepatic follistatin alleviates hyperglycemia

Inactivating hepatic follistatin alleviates hyperglycemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6039237

Inactivating hepatic follistatin alleviates hyperglycemia

About this item

Full title

Inactivating hepatic follistatin alleviates hyperglycemia

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2018-07, Vol.24 (7), p.1058-1069

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Unsuppressed hepatic glucose production (HGP) contributes substantially to glucose intolerance and diabetes, which can be modeled by the genetic inactivation of hepatic insulin receptor substrate 1 (
Irs1
) and
Irs2
(LDKO mice). We previously showed that glucose intolerance in LDKO mice is resolved by hepatic inactivation of the transcr...

Alternative Titles

Full title

Inactivating hepatic follistatin alleviates hyperglycemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6039237

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6039237

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/s41591-018-0048-0

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