Inactivating hepatic follistatin alleviates hyperglycemia
Inactivating hepatic follistatin alleviates hyperglycemia
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Author / Creator
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Unsuppressed hepatic glucose production (HGP) contributes substantially to glucose intolerance and diabetes, which can be modeled by the genetic inactivation of hepatic insulin receptor substrate 1 (
Irs1
) and
Irs2
(LDKO mice). We previously showed that glucose intolerance in LDKO mice is resolved by hepatic inactivation of the transcr...
Alternative Titles
Full title
Inactivating hepatic follistatin alleviates hyperglycemia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6039237
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6039237
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-018-0048-0