Progranulin, lysosomal regulation and neurodegenerative disease
Progranulin, lysosomal regulation and neurodegenerative disease
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Recent studies suggest that progranulin has an important role in lysosome biogenesis and innate immunity in the brain. In this Progress article, Kao and colleagues suggest that progranulin also plays a part in suppressing excessive neuroinflammation during ageing.
The discovery that heterozygous and homozygous mutations in the gene encoding prog...
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Full title
Progranulin, lysosomal regulation and neurodegenerative disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6040832
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6040832
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ISSN
1471-003X
E-ISSN
1471-0048,1469-3178
DOI
10.1038/nrn.2017.36
