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Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases

Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6055183

Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases

About this item

Full title

Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (29), p.E6920-E6926

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Isoxazolines are oral insecticidal drugs currently licensed for ectoparasite control in companion animals. Here we propose their use in humans for the reduction of vector-borne disease incidence. Fluralaner and afoxolaner rapidly killed Anopheles, Aedes, and Culex mosquitoes and Phlebotomus sand flies after feeding on a drug-supplemented blood meal...

Alternative Titles

Full title

Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6055183

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6055183

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1801338115

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