Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13
Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The maintenance of genome stability during mitosis is coordinated by the spindle assembly checkpoint (SAC) through its effector the mitotic checkpoint complex (MCC), an inhibitor of the anaphase-promoting complex (APC/C, also known as the cyclosome)
1
,
2
. Unattached kinetochores control MCC assembly by catalysing a change in the topol...
Alternative Titles
Full title
Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13
Authors, Artists and Contributors
Author / Creator
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6057611
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6057611
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0281-1
