Contributions of BMPR2 Mutations and Extrinsic Factors to Cellular Phenotypes of Pulmonary Arterial...
Contributions of BMPR2 Mutations and Extrinsic Factors to Cellular Phenotypes of Pulmonary Arterial Hypertension Revealed by Induced Pluripotent Stem Cell Modeling
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United States: American Thoracic Society
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Language
English
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Publisher
United States: American Thoracic Society
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Contents
[...]other phenotypes such as inner mitochondrial membrane (IMM) hyperpolarization could not be recapitulated. [...]there is a need to better understand the contribution of BMPR2 mutations to PAH-associated phenotypes and the requirement for other factors in this process. Derivation of iPSC-SMCs and iPSC-ECs that perfectly represent adult PASMCs an...
Alternative Titles
Full title
Contributions of BMPR2 Mutations and Extrinsic Factors to Cellular Phenotypes of Pulmonary Arterial Hypertension Revealed by Induced Pluripotent Stem Cell Modeling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6058985
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6058985
Other Identifiers
ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.201801-0049LE
