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Spleen mediates a distinct hematopoietic progenitor response supporting tumor-promoting myelopoiesis

Spleen mediates a distinct hematopoietic progenitor response supporting tumor-promoting myelopoiesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6063469

Spleen mediates a distinct hematopoietic progenitor response supporting tumor-promoting myelopoiesis

About this item

Full title

Spleen mediates a distinct hematopoietic progenitor response supporting tumor-promoting myelopoiesis

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2018-08, Vol.128 (8), p.3425-3438

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Cancer progression is associated with alterations of intra- and extramedullary hematopoiesis to support a systemic tumor-promoting myeloid response. However, the functional specialty, mechanism, and clinical relevance of extramedullary hematopoiesis (EMH) remain unclear. Here, we showed that the heightened splenic myelopoiesis in tumor-bearing host...

Alternative Titles

Full title

Spleen mediates a distinct hematopoietic progenitor response supporting tumor-promoting myelopoiesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6063469

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6063469

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI97973

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