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GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain

GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6063480

GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain

About this item

Full title

GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2018-08, Vol.128 (8), p.3568-3582

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The mechanisms of pain induction by inflammation have been extensively studied. However, the mechanisms of pain resolution are not fully understood. Here, we report that GPR37, expressed by macrophages (MΦs) but not microglia, contributes to the resolution of inflammatory pain. Neuroprotectin D1 (NPD1) and prosaptide TX14 increase intracellular Ca2...

Alternative Titles

Full title

GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6063480

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6063480

Other Identifiers

ISSN

0021-9738,1558-8238

E-ISSN

1558-8238

DOI

10.1172/JCI99888

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