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Functions of NKG2D in CD8+ T cells: an opportunity for immunotherapy

Functions of NKG2D in CD8+ T cells: an opportunity for immunotherapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6068164

Functions of NKG2D in CD8+ T cells: an opportunity for immunotherapy

About this item

Full title

Functions of NKG2D in CD8+ T cells: an opportunity for immunotherapy

Publisher

London: Nature Publishing Group UK

Journal title

Cellular & molecular immunology, 2018-05, Vol.15 (5), p.470-479

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Natural killer group 2 member D (NKG2D) is a type II transmembrane receptor. NKG2D is present on NK cells in both mice and humans, whereas it is constitutively expressed on CD8
+
T cells in humans but only expressed upon T-cell activation in mice. NKG2D is a promiscuous receptor that recognizes stress-induced surface ligands. In NK cells, NKG...

Alternative Titles

Full title

Functions of NKG2D in CD8+ T cells: an opportunity for immunotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6068164

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6068164

Other Identifiers

ISSN

1672-7681

E-ISSN

2042-0226

DOI

10.1038/cmi.2017.161

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