Genetically engineered cerebral organoids model brain tumor formation
Genetically engineered cerebral organoids model brain tumor formation
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Brain tumors are among the most lethal and devastating cancers. Their study is limited by genetic heterogeneity and the incompleteness of available laboratory models. Three-dimensional organoid culture models offer innovative possibilities for the modeling of human disease. Here we establish a 3D in vitro model called a neoplastic cerebral organoid...
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Full title
Genetically engineered cerebral organoids model brain tumor formation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6071863
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6071863
Other Identifiers
ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/s41592-018-0070-7
