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The Production of Human β-Glucocerebrosidase in Nicotiana benthamiana Root Culture

The Production of Human β-Glucocerebrosidase in Nicotiana benthamiana Root Culture

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6073899

The Production of Human β-Glucocerebrosidase in Nicotiana benthamiana Root Culture

About this item

Full title

The Production of Human β-Glucocerebrosidase in Nicotiana benthamiana Root Culture

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2018-07, Vol.19 (7), p.1972

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Gaucher disease is caused by a deficiency of the enzyme glucocerebrosidase (GCase). Currently, enzyme-replacement therapy using recombinant GCase produced in mammalian cells is considered the most effective treatment. Plants are an attractive alternative host for recombinant protein production due to the low cost of large-scale production and lack...

Alternative Titles

Full title

The Production of Human β-Glucocerebrosidase in Nicotiana benthamiana Root Culture

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6073899

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6073899

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms19071972

How to access this item