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Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6083445

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo

About this item

Full title

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2018-06, Vol.360 (6392), p.981-987

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

More information

Scope and Contents

Contents

High-throughput mapping of cellular differentiation hierarchies from single-cell data promises to empower systematic interrogations of vertebrate development and disease. Here we applied single-cell RNA sequencing to >92,000 cells from zebrafish embryos during the first day of development. Using a graph-based approach, we mapped a cell-state landsc...

Alternative Titles

Full title

Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6083445

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6083445

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aar4362

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