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MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity

MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6085291

MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity

About this item

Full title

MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-08, Vol.8 (1), p.11902-17, Article 11902

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Development of retinal structure and function is controlled by cell type-specific transcription factors and widely expressed co-regulators. The latter includes the mixed-lineage leukemia (MLL) family of histone methyltransferases that catalyze histone H3 lysine 4 di- and tri-methylation associated with gene activation. One such member, MLL1, is wid...

Alternative Titles

Full title

MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6085291

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6085291

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-30355-3

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