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Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition en...

Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition en...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6089754

Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunate‑induced apoptosis

About this item

Full title

Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunate‑induced apoptosis

Publisher

Athens: Spandidos Publications

Journal title

International journal of molecular medicine, 2018-09, Vol.42 (3), p.1295-1304

Language

English

Formats

Publication information

Publisher

Athens: Spandidos Publications

More information

Scope and Contents

Contents

The present study assessed the antitumor effect of artesunate (ART) in vitro and in vivo, as well as its underlying mechanism of action in HCT116 colon cancer cells. An MTT assay, DAPI staining, flow cytometry, western blotting, immunohistochemistry, transmission electron microscopy and TUNEL assay were performed to study the molecular mechanism un...

Alternative Titles

Full title

Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunate‑induced apoptosis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6089754

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6089754

Other Identifiers

ISSN

1107-3756

E-ISSN

1791-244X

DOI

10.3892/ijmm.2018.3712

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