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Coactivator condensation at super-enhancers links phase separation and gene control

Coactivator condensation at super-enhancers links phase separation and gene control

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6092193

Coactivator condensation at super-enhancers links phase separation and gene control

About this item

Full title

Coactivator condensation at super-enhancers links phase separation and gene control

Publisher

United States: The American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2018-07, Vol.361 (6400)

Language

English

Formats

Publication information

Publisher

United States: The American Association for the Advancement of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Many components of eukaryotic transcription machinery—such as transcription factors and cofactors including BRD4, subunits of the Mediator complex, and RNA polymerase II—contain intrinsically disordered low-complexity domains. Now a conceptual framework connecting the nature and behavior of their interactions to their functions in transcription reg...

Alternative Titles

Full title

Coactivator condensation at super-enhancers links phase separation and gene control

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6092193

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6092193

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aar3958

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