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Pro-tumorigenic roles of fibroblast activation protein in cancer: back to the basics

Pro-tumorigenic roles of fibroblast activation protein in cancer: back to the basics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6092565

Pro-tumorigenic roles of fibroblast activation protein in cancer: back to the basics

About this item

Full title

Pro-tumorigenic roles of fibroblast activation protein in cancer: back to the basics

Author / Creator

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2018-08, Vol.37 (32), p.4343-4357

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Fibroblast activation protein (FAP) is a cell-surface serine protease that acts on various hormones and extracellular matrix components. FAP is highly upregulated in a wide variety of cancers, and is often used as a marker for pro-tumorigenic stroma. It has also been proposed as a molecular target of cancer therapies, and, especially in recent year...

Alternative Titles

Full title

Pro-tumorigenic roles of fibroblast activation protein in cancer: back to the basics

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6092565

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6092565

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-018-0275-3

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