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Many-body effect determines the selectivity for Ca2+ and Mg2+ in proteins

Many-body effect determines the selectivity for Ca2+ and Mg2+ in proteins

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6094099

Many-body effect determines the selectivity for Ca2+ and Mg2+ in proteins

About this item

Full title

Many-body effect determines the selectivity for Ca2+ and Mg2+ in proteins

Publisher

National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (32), p.E7495-E7501

Language

English

Formats

Publication information

Publisher

National Academy of Sciences

More information

Scope and Contents

Contents

Calcium ion is a versatile messenger in many cell-signaling processes. To achieve their functions, calcium-binding proteins selectively bind Ca2+ against a background of competing ions such as Mg2+. The high specificity of calcium-binding proteins has been intriguing since Mg2+ has a higher charge density than Ca2+ and is expected to bind more tigh...

Alternative Titles

Full title

Many-body effect determines the selectivity for Ca2+ and Mg2+ in proteins

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6094099

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6094099

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1805049115

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