Many-body effect determines the selectivity for Ca2+ and Mg2+ in proteins
Many-body effect determines the selectivity for Ca2+ and Mg2+ in proteins
About this item
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Author / Creator
Jing, Zhifeng , Liu, Chengwen , Qi, Rui and Ren, Pengyu
Publisher
National Academy of Sciences
Journal title
Language
English
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Publisher
National Academy of Sciences
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Scope and Contents
Contents
Calcium ion is a versatile messenger in many cell-signaling processes. To achieve their functions, calcium-binding proteins selectively bind Ca2+ against a background of competing ions such as Mg2+. The high specificity of calcium-binding proteins has been intriguing since Mg2+ has a higher charge density than Ca2+ and is expected to bind more tigh...
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Full title
Many-body effect determines the selectivity for Ca2+ and Mg2+ in proteins
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6094099
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6094099
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1805049115