Effectiveness of EGFR/HER2-targeted drugs is influenced by the downstream interaction shifts of PTPI...
Effectiveness of EGFR/HER2-targeted drugs is influenced by the downstream interaction shifts of PTPIP51 in HER2-amplified breast cancer cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Breast cancer is the most common female cancerous disease and the second most cause of cancer death in women. About 20–30% of these tumors exhibit an amplification of the HER2/ErbB2 receptor, which is coupled to a more aggressive and invasive growth of the cancer cells. Recently developed tyrosine kinase inhibitors and therapeutic antibodies target...
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Full title
Effectiveness of EGFR/HER2-targeted drugs is influenced by the downstream interaction shifts of PTPIP51 in HER2-amplified breast cancer cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6107558
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6107558
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ISSN
2157-9024
E-ISSN
2157-9024
DOI
10.1038/s41389-018-0075-1
