Insights into the molecular mechanism for hyperpolarization-dependent activation of HCN channels
Insights into the molecular mechanism for hyperpolarization-dependent activation of HCN channels
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Scope and Contents
Contents
Hyperpolarization-activated, cyclic nucleotide-gated (HCN) ion channels are both voltage- and ligand-activated membrane proteins that contribute to electrical excitability and pace-making activity in cardiac and neuronal cells. These channels are members of the voltage-gated Kv channel superfamily and cyclic nucleotide-binding domain subfamily of i...
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Full title
Insights into the molecular mechanism for hyperpolarization-dependent activation of HCN channels
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6112743
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6112743
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1805596115