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Insights into the molecular mechanism for hyperpolarization-dependent activation of HCN channels

Insights into the molecular mechanism for hyperpolarization-dependent activation of HCN channels

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6112743

Insights into the molecular mechanism for hyperpolarization-dependent activation of HCN channels

About this item

Full title

Insights into the molecular mechanism for hyperpolarization-dependent activation of HCN channels

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (34), p.E8086-E8095

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Hyperpolarization-activated, cyclic nucleotide-gated (HCN) ion channels are both voltage- and ligand-activated membrane proteins that contribute to electrical excitability and pace-making activity in cardiac and neuronal cells. These channels are members of the voltage-gated Kv channel superfamily and cyclic nucleotide-binding domain subfamily of i...

Alternative Titles

Full title

Insights into the molecular mechanism for hyperpolarization-dependent activation of HCN channels

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6112743

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6112743

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1805596115

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