Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-...
Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
13-
cis
-retinoic acid (isotretinoin, INN) is an oral pharmaceutical drug used for the treatment of skin acne, and is also a known teratogen. In this study, the molecular mechanisms underlying INN-induced developmental toxicity during early cardiac differentiation were investigated using both human induced pluripotent stem cells (hiPSCs) and...
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Full title
Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6113333
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6113333
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-31192-0
