Rab37 mediates exocytosis of secreted frizzled-related protein 1 to inhibit Wnt signaling and thus s...
Rab37 mediates exocytosis of secreted frizzled-related protein 1 to inhibit Wnt signaling and thus suppress lung cancer stemness
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Recent studies have revealed that dysregulated Rab small GTPase-mediated vesicle trafficking pathways are associated with cancer progression. However, whether any of the Rabs plays a suppressor role in cancer stemness is least explored. Rab37 has been postulated as a tumor suppressive small GTPase for trafficking anti-tumor cargos. Here, we report...
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Rab37 mediates exocytosis of secreted frizzled-related protein 1 to inhibit Wnt signaling and thus suppress lung cancer stemness
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6115395
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6115395
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2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-018-0915-0
