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Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizoph...

Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizoph...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6115412

Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia

About this item

Full title

Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-08, Vol.8 (1), p.13046-14, Article 13046

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Reelin protein (RELN), an extracellular matrix protein, plays multiple roles that range from embryonic neuronal migration to spine formation in the adult brain. Results from genetic studies have suggested that
RELN
is associated with the risk of psychiatric disorders, including schizophrenia (SCZ). We previously identified a novel exonic dele...

Alternative Titles

Full title

Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6115412

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6115412

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-31390-w

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