Rapid and simple detection of Tamiflu-resistant influenza virus: Development of oseltamivir derivati...
Rapid and simple detection of Tamiflu-resistant influenza virus: Development of oseltamivir derivative-based lateral flow biosensor for point-of-care (POC) diagnostics
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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We have developed a novel oseltamivir derivative (oseltamivir hexylthiol; OHT) that exhibits a higher binding affinity for Tamiflu-resistant virus (Tamiflu resistance) than for the wild-type virus (Tamiflu-susceptible virus; WT) as an antibody. First, OHT-modified gold nanoparticles (OHT-GNPs) are used in a simple colorimetric assay as nanoprobes f...
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Full title
Rapid and simple detection of Tamiflu-resistant influenza virus: Development of oseltamivir derivative-based lateral flow biosensor for point-of-care (POC) diagnostics
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6115449
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6115449
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-31311-x